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System Diagram

WARNING: This page is about a different car, the 2008 Lexus LS 600hL. However, it is still accessible from the selected car via links, so may be relevant.
Fig 1: Cruise Control - System Diagram
G05775988Courtesy of © TOYOTA, LICENSE AGREEMENT TMS1002

Communication table 

COMMUNICATION CHART

Sender ECU Receiver ECU Signal Line
Hybrid vehicle control ECU Combination meter CRUISE main indicator light signal CAN
Hybrid vehicle control ECU ECM Throttle motor operation signal CAN
Skid control ECU Hybrid vehicle control ECU Vehicle speed sensor signal CAN
ECM Hybrid vehicle control ECU Throttle position signal CAN